Antibody Glycosylation Engineering

[geminismith]

Antibody glycosylation engineering is a sophisticated technique used to modify the glycan structures attached to the Fc region of antibodies, with the aim of optimizing their therapeutic efficacy. Glycosylation patterns significantly influence an antibody's stability, solubility, and interaction with immune cells. By employing antibody glycosylation engineering, researchers can enhance specific functions such as Antibody-Dependent Cellular Cytotoxicity (ADCC) and Complement-Dependent Cytotoxicity (CDC), tailoring the antibody's action to target diseases more effectively.